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The Assignment (Evidence-Based Project) Part 2: Advanced Levels of Clinical Inquiry and Systematic Reviews Create a 6- to 7-slide PowerPoint presentation in which you do the following: Identify and briefly describe your chosen clinical issue of interest. Describe how you developed a PICO(T) question focused on your chosen clinical issue of interest. Identify the four research databases that you used to conduct your search for the peer-reviewed articles you selected. Provide APA citations of the four relevant peer-reviewed articles at the systematic-reviews level related to your research question. If there are no systematic review level articles or meta-analysis on your topic, then use the highest level of evidence peer reviewed article. Describe the levels of evidence in each of the four peer-reviewed articles you selected, including an explanation of the strengths of using systematic reviews for clinical research. Be specific and provide examples. PICOT QUESTION: In the older population aged between 45-80 with type 2 diabetes and normal blood pressure, does blood pressure-lowering medication help prevent the risk of mortality from cardiovascular diseases more than exercising for thirty minutes out of the day if anti-hypertensives are not used? This assignment will be an approximately 7 slide ppt presentation. Use these suggestions for your slides: 1. cover and title slide with your name, course, date, etc 2. Introduction and purpose for your inquiry 3. PICO(T) question. Please identify . and T 4. The 4 databases you used for your search (You may have new ideas following the suggestions in the forum. Articles should provide RESEARCH for the INTERVENTION you have selected for your inquiry and not just genera in nature. Did the intervention you proposed have an effect on the outcome you named? If you do not already have 4 articles with this detail you will need to search again) You need to USE four databases but your articles no not need to be from each of the 4 databases 5. For each of 4 research articles pertaining to your idea give a brief notation of the level of evidence (your articles should be systematic reviews or highest level of evidence possible). On this slide also be sure to mention the benefit of using a systematic review, even if you do not have a source utilizing one. These articles may be the same as you used for the past assignment if they fit. Some have had to change topics or variables, or your previous articles might not have been high levels of evidence, and therefore you may need new articles. There is reading about “level of evidence”. This is not the purpose or design of the study, it’s the numerical strength of the research and will be graded as level I through level V. Give rationale for your rating. 6. Conclusion slide 7. A slide with all of your resources typed in APA format (double spaced, indented, properly italicized where pertinent according to the new APA manual). You will have 4 references pertaining to research (cited in the ppt and referenced on last slide). By the way the new APA manual does not use “retrieved” nor city of publisher in references. Some in the class are still typing this incorrectly. You do not need to summarize the articles, just identify level of evidence which is based on the methodology. Here is a reminder of levels of evidence for you: Level of evidence (LOE) Description Level I Evidence from a systematic review or meta-analysis of all relevant RCTs (randomized controlled trial) or evidence-based clinical practice guidelines based on systematic reviews of RCTs or three or more RCTs of good quality that have similar results. Level II Evidence obtained from at least one well-designed RCT (. large multi-site RCT). Level III Evidence obtained from well-designed controlled trials without randomization (. quasi-experimental). Level IV Evidence from well-designed case-control or cohort studies. Level V Evidence from systematic reviews of descriptive and qualitative studies (meta-synthesis). Level VI Evidence from a single descriptive or qualitative study. Level VII Evidence from the opinion of authorities and/or reports of expert committees.